IL4R HEK293
CBP74679
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| I. Background | |
| IL4R（白细胞介素-4受体）由IL4R基因编码，是IL-4和IL-13共用的配体结合亚基。它本身以较低亲和力结合配体，需与γc链（形成I型受体）或IL-13Rα1（形成II型受体）结合，才能构成高亲和力功能性受体并激活JAK-STAT6通路，在Th2细胞分化和IgE产生调控中发挥核心作用。 | |
| II. Description | |
| IL4R HEK293 细胞，在 HEK293 细胞的基础上，稳定表达 IL4R。 | |
| III. Introduction | |
| Expressed gene: | IL4R |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10% FBS+5 μg/ml Blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
 Figure 1. Recombinant IL4R HEK293 constitutively expressing IL4R. |
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